Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response |
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| Authors: | Asahina Yasuhiro Izumi Namiki Hirayama Itsuko Tanaka Tomohiro Sato Mitsuaki Yasui Yutaka Komatsu Nobutoshi Umeda Naoki Hosokawa Takanori Ueda Ken Tsuchiya Kaoru Nakanishi Hiroyuki Itakura Jun Kurosaki Masayuki Enomoto Nobuyuki Tasaka Megumi Sakamoto Naoya Miyake Shozo |
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| Affiliation: | Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan. |
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| Abstract: | |
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| Keywords: | CARD, Caspase-recruiting domain Cardif, caspase-recruiting domain adaptor inducing IFN-β G3PDH, glyceraldehyde-3-phosphate dehydrogenase HCV, hepatitis C virus IPS-1, IFN-β promoter stimulator I ISG15, IFN-stimulated gene 15 PEG-IFN, pegylated interferon MDA5, melanoma differentiation associated gene 5 MAVS, mitochondrial antiviral signaling protein NVR, nonvirologic responders PBMC, peripheral blood mononuclear cell RIG-I, retinoic acid-inducible gene I RNF125, ring-finger protein 125 ROC, receiver operator characteristic SVR, sustained viral responder TR, transient responder UBP43, ubiquitin-specific protease 43 USP18, ubiquitin-specific protease 18 VISA, virus-induced signaling adaptor |
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