Islet cell tumor. |
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Authors: | B Fitzpatrick N G Ordo?ez B Mackay |
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Affiliation: | Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030. |
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Abstract: | A case of islet cell tumor occurring in a patient with the multiple endocrine neoplasia type I syndrome is reported. Immunostaining for insulin was strongly positive in the tumor cells. Numerous dense-core granules of endocrine caliber were identified ultrastructurally. Morphometric analysis of the secretory granules in 20 islet cell tumors gave a granule size of 182 +/- 52 nm (mean +/- standard deviation). |
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