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Islet cell tumor.
Authors:B Fitzpatrick  N G Ordo?ez  B Mackay
Affiliation:Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Abstract:
A case of islet cell tumor occurring in a patient with the multiple endocrine neoplasia type I syndrome is reported. Immunostaining for insulin was strongly positive in the tumor cells. Numerous dense-core granules of endocrine caliber were identified ultrastructurally. Morphometric analysis of the secretory granules in 20 islet cell tumors gave a granule size of 182 +/- 52 nm (mean +/- standard deviation).
Keywords:
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