肾脏疾病免疫抑制剂治疗后继发巨细胞病毒(cMV)肺炎的救治研究

目的探讨肾脏疾病免疫抑制剂治疗后巨细胞病毒(cMV)肺炎的急诊救治方法。方法选取我院肾内科2012年-2013年63例肾病综合征免疫抑制剂治疗后继发巨细胞病毒(cMV)肺炎患者,给予相关抗病毒药物治疗并给予对症支持处理;其中35例患者给予球蛋白肌注治疗,观察治疗效果。结果 63例患者中总治愈率为41.03%,死亡6例(9.52%)。两组患者治疗有效率比较差异有统计学意义,P0.05。治愈患者出院后肾功能恢复正常。结论对于肾脏免疫抑制剂治疗后并发的巨细胞病毒肺炎患者应给予抗病毒治疗、调整免疫抑制剂以及辅助呼吸等综合治疗。

Study of emergency treatment of cytomegalovirus (cMV) pneumonia secondary to renal disease after immu-nosuppression

Objective To study the emergency treatment of cytomegalovirus （cMV） pneumonia secondary to renal disease after immunosuppression. Methods 63 patients with nephrotic syndrome immunosuppressant secondary cytomegalovirus （cMV） pneumonia were selected to giveantiviral drugs and related supportive treatment, and 35 of them were additionally treated with globulin intramuscular injection. Results The total cure rate was 41.03%, and 6 cases of death reported （9. 52% ）. The total effective rate showed significant differences between the two groups （P 〈0. 05 ）. Their renal function returned to normal after discharge. Conclusion Patients with cytomegalovirus （cMV） pneumonia secondary to renal disease after immunosuppression should be given antiviral treatment, adjust the immune inhibitors and assist breathing comprehensive treatment.