导丝分割与胸腔注射尿激酶治疗结核性胸膜炎

目的对弹性导丝分割与胸腔注入尿激酶在治疗多发分隔结核性胸腔积液的临床疗效进行比较。方法选取多发分隔结核性胸腔积液患者98例,分为a组(导丝组)、b组(尿激酶组)及c组(合用组),观察三组胸腔积液好转天数、胸腔积液引流量及胸膜反应发生率并进行比较。结果胸腔积液好转天数、胸水引流量a组与b组及a组与c组之间有统计学差异(P0.05),而b组与c组无统计学差异(P0.05)。操作出现胸膜反应a组与c组无统计学差异(P0.05),而a组与b组、b组与c组之间有统计学差异(P0.05)。结论弹性导丝分割是治疗结核性胸腔积液的有效治疗方法,但胸膜反应发生率高,胸腔注入尿激酶带来更多的胸腔积液引流量,两种方法合用并无优势。

Comparison between guide wire diremption and intrapleural injection with urokinase in the treatment of tu-berculosis pleurisy

Objective To compare the curative effect between guide wire diremption and intrapleural injec-tion with urokinase in the treatment of tuberculosis pleurisy. Methods 96 patients with tuberculous separated pleural effusion were randomly divided into the group A （ elastic guide wire） , the group B （ urokinase） and the group C （ in both ways） . The number of days that pleural effusion got better, pleural effusion drainage and pleural reaction rate were observed. Results There were significant differences in recovery time, pleural effusion drainage and pleural re-action between the group A vs the group B and the group A vs the group C, but there was no significant difference be-tween the group B and the group C. There was significant difference in the incidence of pleural reaction between the group A vs the group B and the group C vs the group B, but there was no significant difference between the group A and the group C. Conclusion Elastic guide wire diremption is an effective method for the treatment of tuberculous pleural effusion, but pleural reaction rate is high. The intrapleural injection of urokinase has more pleural effusion drainage, and the combination of two methods has no advantage.