Fluorimetric analysis of mebendazole and flubendazole with hydrogen peroxide |
| |
| Authors: | Baeyens W Fattah F A De Moerloose P |
| |
| Affiliation: | Department of Pharmaceutical Chemistry and Drug Quality Control, Faculty of Pharmaceutical Sciences, State University of Ghent, Harelbekestraat 72, B-9000-Ghent, Belgium. |
| |
| Abstract: | ![]()
Analytically useful fluorescence was obtained from mebendazole and flubendazole after reaction with hydrogen peroxide in alkaline solution. The fluorescence produced (lambda(ex) = 300 nm; lambda(em) = 360 nm) is stable and concentrations of 0.1 mug ml(-1) can be determined. The method has been applied to the analysis of some commercially available anthelmintic preparations. |
| |
| Keywords: | Fluorescence spectroscopy mebendazole flubendazole hydrogen peroxide derivatives anthelmintics. |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
