多发性骨髓瘤35例临床分析

分析多发性骨髓瘤３５例，年龄多大于５５岁。首发症状以骨痛多见，免疫分型以ＩｇＧ为主，均存在骨质疏松、溶骨性改变，颅骨多见。病理性骨折多见于腰椎。采用改良Ｍ２方案化疗，８３．９％达缓解。死亡２４例，主要死于肾功能衰竭，平均生存期４４．８个月。

Clinical analysis of 35 cases of multiple myeloma

patients with multiple myeloma were studied. 25 patients were older than 55 years of age(42. 9%). The initial symptom was bone pain mainly, which occurred in 26 patients(74.3%).The immunological type is mainly IgG(60%). All patients suffered from osteoporosis, osteolytic lesions (74. 3%)and pathologic fracture (44. 8%)were found in skull and lumbar vertebrae mainly, respectively. All patients were treated with improved M2 chemotherapy. The remission rate was 85.7%. 24 patients died. The main cause of death was renal faiture(28.6%). The average survival duration was 4. 8 months (18 to 78 months).