| 蜂地麻滴眼液的制备及质量控制 |
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| 引用本文： | 孙艳,周晓兵,谢牧牧.蜂地麻滴眼液的制备及质量控制[J].中国现代医学杂志,2008,18(11). |
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| 作者姓名： | 孙艳 周晓兵 谢牧牧 |
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| 作者单位： | 中国人民解放军总医院,药品保障中心,北京,100853 |
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| 摘 要： | 目的制备蜂地麻滴眼液，并建立其质量标准。方法根据制备工艺制备滴眼液，用薄层色谱法进行鉴别，用高效液相色谱法进行含量测定。结果受试品和对照品的薄层特征性斑点一致，盐酸丁卡因的平均回收率为100．25％，RSD=0．75％，盐酸麻黄碱的平均回收率为99．57％，RSD=0．91％。结论蜂地麻滴眼液的制备方法简便，质量可控。
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| 关 键 词： | 滴眼液 制备 质量控制 薄层色谱法 HPLC法 滴眼液 质量控制 eye drops 质量可控 盐酸麻黄碱 平均回收率 盐酸丁卡因 斑点 特征 薄层色谱法 对照品 结果 含量测定 高效液相色谱法 鉴别 工艺制备 方法 质量标准 |
Rreparation of Fengdima eye drops |
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| SUN Yan,ZHOU Xiao-bing,XIE Mu-mu.Rreparation of Fengdima eye drops[J].China Journal of Modern Medicine,2008,18(11). |
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| Authors: | SUN Yan ZHOU Xiao-bing XIE Mu-mu |
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| Institution: | SUN Yan,ZHOU Xiao-bing,XIE Mu-mu (Department of Pharmacy,Chinese PLA General Hospital,Beijing 100853,P.R.China) |
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| Abstract: | Objective] To prepare Fengdima eye drops, and to establish its quality criterion by studying the methods of quality controlling. Methods] The eye drops was prepared according to the technology, its contents was identified by TLC methods and determined by HPLC methods. Results] The characteristic spots of tested contents was consistent with referenced contents, the average recovery of tetracaine hydrochloride was 100.25%, RSD=0.75%, the average recovery of Ephedrine Hydrochloride was 99.57%, RSD=0.91%. C... |
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| Keywords: | eye drops preparation quality control TLC HPLC |
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