慢性咳嗽68例临床分析

目的 分析慢性咳嗽患者的病因分布。方法 对68例慢性咳嗽患者进行前瞻性研究。常规行X线胸片、肺功能、食道内镜、痰检查及血液学检查。必要时查支气管激发试验、24h食道PH值监测、鼻窦CT、纤维支气管镜及纤维鼻咽镜。根据临床表现、检查结果及特异性治疗疗效作最后诊断。结果 病因依次为咳嗽变异型哮喘30例，44．1％、鼻后滴流综合征21例，30．9％；胃食管反流病13例，19．1％；支气管结核2例，2，9％；真菌感染1例，1．5％；嗜酸细胞性支气管炎1例，1．5％。结论 慢性咳嗽最常见的病因为咳嗽变异型哮喘、鼻后滴流综合征及胃食管反流病。

Clinical analysis of 68 patients with chronic cough

Objective To analyse the causes of chronic cough. Methods A prospective study of 68 patients with chronic cough was performed. the diagnosis workup included chest x-ray, pulmonary function test, esophagus endoscope, sputum examination, hematology test, after these routine test, brinchial provocation test, Dual-probe 24-hour ambulatory pH monitoring, accessory nasal cavity CT, bronchofibroscope, nasopharyngo-fiberoscope were selected when needed. The diagnosis was based on both clinical, radiologic and laboratory findings and the response to therapy. Results The most common causative factors were cough variation asthma, postnasal drip syndrome, gastroesophageal reflux disease. The common causative factors were cough variant asthma (CVA) 44.1%, postnasal drip syndrome (PNDs) 30.9%, Gastroesophageal reflux disease (GRD)19.1%,bronchial tuberculosis 2.9%, spore infection in working place 1.5%,eosinophilic bronchitis (EB) 1.5%. Conclusion CVA, PNDs and GRD are the three most common causative factors.