Treatment of primary g lioblastoma multiforme with c e tuximab, r adiotherapy and t emozolomide (GERT) – phase I/II trial: study protocol |
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Authors: | Stephanie E Combs Steffen Heeger Renate Haselmann Lutz Edler Jürgen Debus Daniela Schulz-Ertner |
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Affiliation: | (1) Department of Radiation Oncology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany;(2) Department of Biostatistics, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany;(3) Merck KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany |
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Abstract: |
Background The implementation of combined radiochemotherapy (RCHT) with temozolomide (TMZ) has lead to a significant increase in overall survival times in patients with Glioblastoma multiforme (GBM), however, outcome still remains unsatisfactory. |
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