| 661例抗肿瘤药不良反应报告回顾性分析 |
| |
| 引用本文： | 刘琳琳,孙言才,姜玲,沈爱宗,杜德才,史天陆. 661例抗肿瘤药不良反应报告回顾性分析[J]. 药物流行病学杂志, 2011, 0(5): 229-232 |
| |
| 作者姓名： | 刘琳琳 孙言才 姜玲 沈爱宗 杜德才 史天陆 |
| |
| 作者单位： | 安徽医科大学附属省立医院; |
| |
| 摘 要： | 目的：探讨抗肿瘤药不良反应发生的特点，为临床安全用药提供参考。方法：收集某院2004～2008年的抗肿瘤药不良反应报告表661例，对抗肿瘤药不良反应所涉及的患者性别、年龄、药品、给药途径、临床表现、级别等项目进行定量分析。结果：661例报告表中，男430例（65．05％），女231例（34．95％），60岁以上的患者发生药品不良反应（ADR）191例（38．43％）；涉及64种抗肿瘤药，涉及怀疑药物共计1145例次；居前3位的药物是顺铂（210例次）、氟尿嘧啶（135例次）、奥沙利铂（124例次）；静脉注射给药1027例次（89．69％）；涉及ADR临床症状共计1566例次，消化系统损害773例次（49．36％）居首位；发生新的、严重的ADR共242例，占36．61％。结论：收集整理抗肿瘤药不良反应报告，定量分析、综合评价其基本信息，有助于促进抗肿瘤药临床合理应用，保障患者安全用药。
|
| 关 键 词： | 抗肿瘤药 药品不良反应 回顾性分析 |
| 收稿时间： | 2010-11-11 |
| 修稿时间： | 2011-03-04 |
Retrospective Analysis of 661 Cases of Adverse Drug Reactions Induced by Antitumor Drugs |
| |
| Liu Linlin,Sun Yancai,Jiang Ling,Shen Aizong,Du Decai and Shi Tianlu. Retrospective Analysis of 661 Cases of Adverse Drug Reactions Induced by Antitumor Drugs[J]. Chinese Journal of Pharmacoepidemiology, 2011, 0(5): 229-232 |
| |
| Authors: | Liu Linlin Sun Yancai Jiang Ling Shen Aizong Du Decai Shi Tianlu |
| |
| Affiliation: | Liu Linlin,Sun Yancai,Jiang Ling,Shen Aizong,Du Decai,Shi Tianlu Provincial Hospital Affiliated to Anhui Medical University,Hefei 230001,China |
| |
| Abstract: | Objective:To probe into the characteristics of adverse drug reactions(ADR)caused by antitumor drugs and to provide some rational clinical guidance.Method:661 reports of adverse reactions caused by antitumor drugs were collected in a 3A-Grade Hospital from January 2004 to December 2008 and statistically analyzed in respect of patients' sex and age,involved drugs,routes of administration,clinical manifestations,rating of correlated factors,etc.Result: Of the 661 cases,65.5%were male cases(430)and 34.95%,femal... |
| |
| Keywords: | Antitumor drug Adverse drug reactions Retrospective Analysis |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
