超声引导下微波消融治疗胃肠神经内分泌肿瘤的应用研究

目的 探讨超声引导下微波消融治疗胃肠内分泌肿瘤的疗效.方法 选取90例胃肠神经内分泌肿瘤,在超声引导下行微波消融治疗,分析其效果,不良反应及并发症,患者的生存情况及影响因素.结果 治疗前超声显示肿瘤内均有血流信号,治疗后血流信号减少或消失(P<0.05);有2例出现发热,5例进针处出现疼痛,对症治疗后消失,不良反应轻微(P<0.05);有40例死亡,50例存活,分化程度、肿瘤数目、肿瘤大小、复发转移均是影响胃肠神经内分泌肿患者生存情况的独立危险因素(P<0.05).结论 在超声引导下微波消融治疗胃肠神经内分泌肿瘤,效果较好,不良反应轻微,患者的生存情况与肿瘤的分化程度、肿瘤的数目、肿瘤大小、复发转移有关.

Study of Ultrasound-guided Microwave Ablation for Gastrointestinal Neuroendocrine Tumor

Objective To investigate the efficacy of ultrasound-guided microwave ablation in the treatment of gastrointes-tinal endocrine tumors. Methods 90 cases of gastrointestinal neuroendocrine tumor were treated with ultrasound-guided micro-wave ablation,efficacy,adverse reactions and complications,patient's survival condition and influencing factors were analyzed. Re-sults Ultrasound showed blood flow signals in tumor before the treatment,blood flow signal reduced or disappeared after treat-ment (P<0. 05);There were 2 cases of fever,5 cases had the needle pain,and disappeared after symptomatic treatment,slight adverse reactions (P<0. 05);There were 40 deaths,50 cases of survival;degree of differentiation,tumor number,tumor size,re-currence and metastasis were independent risk factors affecting survival in patients with gastrointestinal neuroendocrine tumor ( P<0. 05). Conclusion Ultrasound guided microwave ablation for gastrointestinal neuroendocrine tumor is effective with minor ad-verse reactions,the survival of patients is related with tumor differentiation,tumor number,tumor size,recurrence and metastasis.