| 康莱特联合GP方案治疗晚期非小细胞肺癌临床疗效观察 |
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| 引用本文： | 刘东梅,张剑,张伟,何文婧,郝光军. 康莱特联合GP方案治疗晚期非小细胞肺癌临床疗效观察[J]. 现代肿瘤医学, 2017, 0(22): 3626-3628. DOI: 10.3969/j.issn.1672-4992.2017.22.020 |
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| 作者姓名： | 刘东梅 张剑 张伟 何文婧 郝光军 |
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| 作者单位： | 榆林市第一医院暨延安大学第二附属医院,陕西 榆林,719000 |
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| 摘 要： | 目的:观察康莱特联合GP方案(吉西他滨+顺铂)治疗晚期非小细胞肺癌患者的有效性.方法:将72例晚期非小细胞肺癌患者随机分为试验组和对照组,对照组予GP方案化疗,试验组予GP化疗方案+康莱特联合治疗,比较两组治疗有效率、对生活质量影响及肿瘤标志物水平.结果:两组间治疗有效率相当,差异无统计学意义(P>0.05);试验组KPS评分改善优于对照组,差异有统计学意义(P<0.05);试验组肿瘤标志物水平低于对照组.结论:康莱特联合GP方案化疗不影响晚期非小细胞肺癌患者治疗有效率,但可降低患者血清糖链抗原CA-125、神经烯醇化酯酶(NSE)水平,明显改善患者生活质量.
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| 关 键 词： | 康莱特 吉西他滨 顺铂 非小细胞性肺癌 |
Kanglaite combined with GP and non small cell lung cancer |
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| Liu Dongmei,Zhang Jian,Zhang Wei,He Wenjing,Hao Guangjun. Kanglaite combined with GP and non small cell lung cancer[J]. Journal of Modern Oncology, 2017, 0(22): 3626-3628. DOI: 10.3969/j.issn.1672-4992.2017.22.020 |
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| Authors: | Liu Dongmei Zhang Jian Zhang Wei He Wenjing Hao Guangjun |
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| Abstract: | Objective:To analysis Kanglaite combined with GP regimen (Gemcitabine + Cisplatin)and GP regi-men only in the treatment of advanced non small cell lung cancer(NSCLC),aims to estimate the validity of Kanglaite in treating NSCLC.Methods:The data of 72 cases of advanced NSCLC patients were randomly divided into experi-mental group and control group,control group received GP chemotherapy,the test group received GP chemotherapy +Kanglaite combined treatment,efficiency and effect on quality of life of two groups were compared.Results:Effective rate of Kanglaite + GP was equal to GP in treating NSCLC(P > 0.05).Life quality improved significantly in Kanglaite+ GP group(P< 0.05).Conclusion:Kanglaite significantly improved life quality of NSCLC patients.It's worthy of clinical promotion. |
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| Keywords: | Kanglaite Gemcitabine Cisplatin non small cell lung cancer |
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