38例男性乳腺癌临床分析

目的：探讨男性乳腺癌临床特点、治疗及预后。方法：选择1980年～2007年收治的38例男性乳腺癌患者，并对其发病特点、诊治经过及预后进行回顾性分析，采用Kaplan-Meier法计算生存率，绘制生存曲线，并应用log—rank法对生存曲线间的差异进行检验。结果：38例患者中2例失访，其余患者随访时间为2个月-15年，5年总体生存率为65．0％。结论：与女性乳腺癌相比，男性乳腺癌有其自己的特性，在治疗上采用以手术为主，术后辅以放疗、化疗及内分泌治疗的综合治疗。其原发肿瘤的大小及是否浸润周围皮肤和患者的TNM分期是影响男性乳腺癌预后的主要因素。

Clinical analysis of 38 cases with male breast cancer

Objective To study the clinical characteristics, diagnostic and therapic method, and prognosis of male breast cancer. Method Thirty-three patients who were diagnosed as male breast cancer and treated in the First Hospital of Jilin University from 1980 to 2007 were analy zed retrospectirely Kaplan-Meier Product Limit method was used to calculate the survival rate. Result Two cases of 38 patients were lost, and the others' follow-up times were from 2 months to 15 years. The overall survival rate was 65.0%.Conclusion Male breast cancer has special clinical characteristics. The therapy of male breast cancer must be a systematic treatment including surgery, radiotherapy, chemotherapy, and endocrine therapy. The major prognostic factors are primary tumor size, and TNM stage.