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Miller Fisher Syndrome Following Vaccination against SARS-CoV-2
Authors:Makoto Yamakawa  Keiichi Nakahara  Toshihito Nakanishi  Toshiya Nomura  Mitsuharu Ueda
Affiliation:1.Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Japan; 2.Department of Neurology, Kumamoto Kinoh Hospital, Japan
Abstract:
After BNT162b2 messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination, a 30-year-old man developed bilateral lateral gaze palsy, diplopia, absent tendon reflexes, and ataxic gait. Serum anti-GQ1b and anti-GT1a immunoglobulin G (IgG) antibodies were strongly positive. Based on those findings, he was diagnosed with Miller Fisher syndrome (MFS). Intravenous immunoglobulin therapy was administered, and his symptoms fully recovered within approximately 3 months. To the best of our knowledge, this is the first report to describe the development of MFS after COVID-19 mRNA vaccination.
Keywords:Miller Fisher syndrome   vaccine   COVID-19   SARS-CoV-2   adverse event
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