| 胃肠道间质瘤32例临床病理分析及免疫组化研究 |
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| 引用本文： | 孙兆田,刘业东,鲍东梅. 胃肠道间质瘤32例临床病理分析及免疫组化研究[J]. 临床消化病杂志, 2003, 15(5): 212-214 |
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| 作者姓名： | 孙兆田 刘业东 鲍东梅 |
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| 作者单位： | 济南市第四人民医院病理科,济南,250031;北京大学人民医院病理科,北京,100440 |
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| 摘 要： | 目的：探讨胃肠道间质瘤的临床病理及免疫组化特点和诊断标准。方法：对32例胃肠道间质瘤进行常规病理检查及免疫组化染色。结果：胃肠道间质瘤由梭形细胞和上皮样细胞组成,大多数病例CD117和CD34标记阳性。结论：胃肠道间质瘤是胃肠道常见的非上皮性肿瘤,缺乏定向分化。CD117、CD34标记阳性对胃肠道间质瘤的诊断具有重要的价值。
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| 关 键 词： | 胃肠道间质瘤 免疫组织化学 CD117 CD34 |
| 文章编号： | 1005-541X(2003)05-214-03 |
| 修稿时间： | 2003-04-28 |
A Clinicopathologic and Immunohistochemical Study of 32 Cases of Gastrointestinal Stromal Tumors |
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| Sun Zhao-tian,Liu Ye-dong,Bao Dong-mei. A Clinicopathologic and Immunohistochemical Study of 32 Cases of Gastrointestinal Stromal Tumors[J]. Chinese Journal of Clinical Gastroenterology, 2003, 15(5): 212-214 |
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| Authors: | Sun Zhao-tian Liu Ye-dong Bao Dong-mei |
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| Affiliation: | Sun Zhao-tian,Liu Ye-dong,Bao Dong-meiDepartment of Pathology,the Fourthe People's Hospital of Jinan city,Jinan 250031 |
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| Abstract: | Purpose: To Investigate the clinicopathologic and immunohistochemical features and diagnostic criteria of gastrointestinal stromal tumors(GIST). Methods: 32 cases of GIST were studied by routine stain and immunohistochemistry.Results:The GISTs showed two basic cell types spindle and epithelioid;in most tumor cells that were positivery stained for CD117 and CD34. Conclusion: GIST which have no evidenced of specific differentiation constitute the largest category of nonethelial neoplasms of gastrointestinal tract.The expression of CD117 and CD34 play an important role in diagnosis of GIST. |
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| Keywords: | Gastrointestinal stromal tumors Immunohistochemistry CD117 CD34 |
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