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Ocular Complications in Influenza Virus Infection |
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| Authors: | Joanna Brydak-Godowska Monika Turczyńska Lidia B Brydak Dariusz K?cik |
| Institution: | 1. Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland;2. Director of the National Influenza Centre, Director of the Department of Influenza Research, National Institute of Public Health – National Institute of Hygiene, Warsaw, Poland |
| Abstract: | Purpose: To describe a case series of ocular complications associated with upper respiratory tract infections. Methods: Four patients aged 21–61 years (three females, one male) had confirmed ocular complications connected with a general upper respiratory tract infection with myalgia and fever. Ophthalmological examination, including a visual acuity test, a slit-lamp exam, intraocular pressure measurements, fluorescein and indocyanine green angiography, optical coherence tomography (OCT), and diagnostic tests for influenza were performed in the patients (RT-PCR, HAI). Results: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) was diagnosed in three patients and serous macular detachment (SME) in one. Influenza virus infection was confirmed by molecular biological methods (RT-PCR) or the hemagglutination inhibition test (HAI) in two patients. All patients were treated with systemic prednisone. Conclusion: A coincidence between APMPPE and SME epitheliopathy and influenza virus infection was observed in different months of a given epidemic season. |
| Keywords: | Acute posterior multifocal placoid pigment epitheliopathy angiography influenza infection optical coherence tomography serous retinal detachment |