清热利湿法治疗糖尿病足的临床研究

目的探讨清热利湿法治疗糖尿病足的疗效。方法将62例糖尿病足感染患者随机分为治疗组34例,采用清热利湿方剂配合抗生素治疗,对照组28例采用抗生素治疗,分别治疗7~14天后观察疗效。结果2组临床有效率、溃疡愈合状况、血糖指标等比较差异无显著意义(P>0.05)。清热利湿药物联合抗生素在改善糖尿病足麻木、疼痛、皮温、皮色、踝/肱指数等方面优于单用抗生素(P<0.05)。2组治疗前后足背动脉搏动方面疗效不确切。除了部分轻、中度患者病情波动外,治疗期间均有良好的耐受。结论在治疗糖尿病足感染方面,清热利湿方与通常应用的抗生素疗效相近,在改善症状方面优于抗生素。

Clinical observation of diabetic foot treated by clearing heat and removing dampness therapy

Objective To investigate the therapeutic effect of clearing heat and removing dampness method on diabetic foot.Methods 62 patients with diabetic foot infection were randomly divided into treatment group and control group.34 patients in treatment group were treated by clearing heat and removing dampness method combined with antibiotics;28 patients in control group were treated only by antibiotics. Therapeutic effect in both groups was observed 7,14 days later.Results There was no significant difference in clinical effective rate, healing state of the ulcer and blood sugar index between two groups (P>0.05).The treatment group was superior to control group in amelioration of acroanesthesia, pain, skin temperature,skin color,A/B index (P<0.05).The effect of improving the pulse of dorsal artery of foot in both groups was not certain.The patients in both groups were well tolerant,except for part of patients with adverse reactions of mild or moderate degree.Conclusion The clinical efficacy and safety of clearing heat and removing dampness method is similar to that of routine administration of antibiotics in treating diabetic foot infection.The former is superior to antibiotics in improving clinical symptoms.