1例多重耐药鲍曼不动杆菌颅内感染病例讨论

目的通过对1例多重耐药鲍曼不动杆菌颅内感染患者成功抗感染治疗的分析讨论，促进专科临床药师树立对专科治疗、营养、生命支持等治疗的整体观理念。方法分析讨论1例多重耐药的鲍曼不动杆菌颅内感染患者抗感染治疗过程。结果美罗培南虽然药敏显示耐药，但前期治疗有效，根据其药动学／药效学（PK／PD），持续泵入，延长给药时间，加上甘露醇降低颅内压等治疗，抗感染治疗效果明显。结论抗感染效果不仅仅由抗菌药物决定，有效的综合治疗诸如患者的营养改善、内环境稳定等决定抗感染最终的治疗效果。

Discussion on Pharmaceutical Care for a Patient with Multi-drug Resistant Acinetobacter Baumannnii Infection

OBJECTIVE Analysis of one case of multidrug-resistsnt Acinetobacter Bauman anti-infection treatment of intracranial infection, help clinical pharmacists to establish the overall concept of treatment such as nutritional therapy, life support teantment. METHODS Analysis the treatment of an case of Acinetobacter Bauman anti-infection treatment of intracranial infection. RESULTS Mannitol to lower intracranial pressure, prolonged infusion administration and another effective treatments improve the anti infection effects. CONCLUSION Anti-infective effect depends on many aspects of effective treatments.