| 小鼠类巨噬细胞系MMC-1生物学特性的缩时显微电影分析 |
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| 引用本文： | 王瑞瑜,何申,王春景,王德斌.小鼠类巨噬细胞系MMC-1生物学特性的缩时显微电影分析[J].中国医学科学院学报,1991(1). |
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| 作者姓名： | 王瑞瑜 何申 王春景 王德斌 |
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| 作者单位： | 中国医学科学院基础医学研究所，中国医学科学院基础医学研究所，中国医学科学院基础医学研究所，中国医学科学院肿瘤研究所 北京，北京，北京 |
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| 摘 要： | 用缩时显微电影技术记录小鼠类巨噬细胞系MMC-1并进行分析。结果证明该细胞系除具有一般培养细胞的性质,如铺开、极性、接触抑制及有丝分裂外,还具有巨噬细胞吞噬及玫瑰花结形成特性。此外,还观察到1个饱食后的MMC-1细胞向周围前进中的红细胞伸出手指样丝状伪足,在伪足与红细胞接触处,红细胞碎片沿伪足移向MMC-1细胞体而溶解。
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| 关 键 词： | 缩时显微电影 巨噬细胞 吞噬 |
Time-lapse Microcinematographical Analysis of the Biological Characteristics of a Macrophage-like Cell Line-MMC-1 |
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| Wang Ruiyu.Time-lapse Microcinematographical Analysis of the Biological Characteristics of a Macrophage-like Cell Line-MMC-1[J].Acta Academiae Medicinae Sinicae,1991(1). |
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| Authors: | Wang Ruiyu |
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| Abstract: | By using tine-lapse mcroeinetnatography, we recorded and conducted an analysis of the macrophage-like cell line MMC-1, including observations of the spreading, polarity, contact inhibition and mitosis common to cultured cells as well as the properties of phagocytosis and rosette formation unique to macrophage. We also found an MMC-1 cell which, after feeding, still stretched its finger-like filopodia towards surrounding red blood cells. The filopodia extended as red blood cells moved towards them. At the point of contact, red blood cell fragments were seen moving towards the cell body along the filopodia; a kind of cytolysis was progressing. |
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| Keywords: | time-lapse microciDematography acrop hage phagocytosis |
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