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丝裂霉素C在治疗难治性青光眼的临床应用
引用本文:彭伟,李劲,刘志远,朱格非. 丝裂霉素C在治疗难治性青光眼的临床应用[J]. 中外医疗, 2009, 28(23): 183-184
作者姓名:彭伟  李劲  刘志远  朱格非
作者单位:广东省深圳市人民医院眼科,广东深圳,518020
摘    要:目的观察小梁切除术中联合丝裂霉素C(MMC)治疗难治性青光眼的疗效。方法小果切除术中联合丝裂霉素C治疗18例18眼难治性青光眼,术后随访1年,观察其临床疗效及手术并发症。结果手术成功率为83。3%;眼压由术前的(45.17±12.01)mmHg降至术后的(16.89±3.42)mmHg。采用配对f检验差异有统计学意义(P〈0.01)。术后并发症为滤过泡漏,前房出血,浅前房。结论小梁切除术联合丝裂霉素C手术治疗难治性青光眼是一种相对安全有效的治疗方法。

关 键 词:丝裂霉素C  难治性青光眼  小梁切除术

Clinical Application of Mitomycin C for Refractory Glaucoma
Affiliation:PEMG Wei LI Jing LIU Zhiyuan et al (Department of Ophthalmology, Shenzhen people's hospital, Shenzhen 518020, China)
Abstract:Objective To observe the therapeutic effects of trabeculectomy combined with mitomycin C on the refractory glaucoma. Methods A study of clinical effect and complications were conducted on 18 eyes from 18 patients with refractory glaucoma with oneyear follow-up.Results The success rate of surgery was 83.3% .The average IOP decreased from the preoperative(45.17± 12.01) mmHg to the postoperative( 16.89±3.42)mmHg(P〈0.01 ) .The complications included filtering bleb leakage, hyphema,flat anterior chamber.Conclusion trabeculectomy combined with mitomycin C may be effective and safe for treating refractory glaucoma.
Keywords:Refractory glaucoma  Trabeculectomy  Mitomycin C
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