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内脂素在MIN6胰岛β细胞的表达及葡萄糖和棕榈酸对其表达的影响
引用本文:程群,彭永德,董维平,王煜非,王育璠,丁晓颖. 内脂素在MIN6胰岛β细胞的表达及葡萄糖和棕榈酸对其表达的影响[J]. 中华内分泌代谢杂志, 2007, 25(1): 318-319
作者姓名:程群  彭永德  董维平  王煜非  王育璠  丁晓颖
作者单位:上海交通大学附属第一人民医院内分泌科,200080;上海交通大学附属第一人民医院糖尿病研究室,200080;
基金项目:上海市科委引导计划项目上海市科学技术委员会专项基金重点项目
摘    要:Visfatin was expressed in rat anti mouse islets,as well as in MIN6 cells. The visfatin expression was affected by various concentrations of environmental glucose (5.5 and 33.3 mmoL/L) and palmitate(0.5 mmol/L). As compared with low-level glucose medium (5.5 mmol/L, 1.0±0.11) , visfatin expression increased in media with high glucose and palmitate (1.32 ±0. 18, 1. 33±0. 15,1.72±0.27, all P<0. 05). The result suggests that visfatin seems to be involved in the regulation of insulin secretion.

关 键 词:内脂素   葡萄糖   棕榈酸   胰岛素分泌   

Expression of visfatin in MIN6 islet IS-cells and effects of glucose and palmitate
CHENG Qun,PENG Yong-de,DONG Wei-ping,WANG Yu-fei,WANG Yu-fan,DING Xiao-ying. Expression of visfatin in MIN6 islet IS-cells and effects of glucose and palmitate[J]. Chinese Journal of Endocrinology and Metabolism, 2007, 25(1): 318-319
Authors:CHENG Qun  PENG Yong-de  DONG Wei-ping  WANG Yu-fei  WANG Yu-fan  DING Xiao-ying
Abstract:
Keywords:VisfatinGlucosePalmitateInsulin secretion
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