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K-Cell Activity in Aplastic Anaemia |
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| Authors: | J. C. Voltarelli R. P. Falcão I. F. Carvalho C. Bottura |
| Affiliation: | Divisions of Haematology and Clinical Immunology, Department of Clinical Medicine, School of Medicine, Ribeirão Preto, University of São Paulo, Brazil |
| Abstract: | K-cell activity was measured by specific cytotoxicity and cytotoxic capacity in 29 patients with aplastic anaemia. 9 patients had a reduction of the specific cytotoxicity and 12 had a decreased cytotoxic capacity. The decreased cytotoxic capacity correlates with the severity of aplastic anaemia. Some of the possible causes of the reduction of this activity were investigated. |
| Keywords: | antibody-dependent cell cytotoxicity antilymphocyte antibodies aplastic anaemia immune complexes killer cells |