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血液高凝分子标志物在脑血栓形成各期的动态变化及临床意义
引用本文:闫俊杰,徐荣慧,佟晓艳,刘杰,耿志伟,于宏玲. 血液高凝分子标志物在脑血栓形成各期的动态变化及临床意义[J]. 黑龙江医学, 2004, 28(4): 265-266
作者姓名:闫俊杰  徐荣慧  佟晓艳  刘杰  耿志伟  于宏玲
作者单位:大庆油田总医院神经内科,黑龙江,大庆,163000;大庆市第四医院内分泌科,黑龙江,大庆,163000
摘    要:
目的 探讨血液高凝分子标志物在脑血栓形成各期的动态改变及临床应用价值。方法 选择 36例脑血栓形成期患者为研究组 ,并设对照组 2 5例。采晨血 6mL ,对研究组分别在急性期、亚急性期和慢性期3个时相各采血 1次 ,应用ELDSA法测定血浆FPA浓度 ,采用双抗体夹心ELDSA测定DD浓度。将其结果进行统计学处理。结果 脑血栓形成各期血浆FPA浓度均显著高于对照组 ,脑血栓形成中各期无显著差异。DD浓度亦显著高于对照组 ,但亚急性期高于急性期 ,慢性期与急性期无显著性差异。结论 测定血液高凝分子标志物对诊断脑血栓形成有一定实用价值

关 键 词:神经内科学  血液高凝分子标志物  FPA  DD  脑血栓形成
文章编号:1004-5775(2004)04-0265-02
修稿时间:2004-02-20

Development Cange and Clinical Significance of Hypercoagulable Molecular Marer in Varied Stages of Cerebral Trombosis
YAN Jun-jie,XU Rong-hui,DONG Xiao-yan,et al.. Development Cange and Clinical Significance of Hypercoagulable Molecular Marer in Varied Stages of Cerebral Trombosis[J]. Heilongjiang Medical Journal, 2004, 28(4): 265-266
Authors:YAN Jun-jie  XU Rong-hui  DONG Xiao-yan  et al.
Abstract:
Objective To discuss the development change and clinical significance of hypercoagulable molecular marker (HMM) in varied stages of cerebral thrombosis (CT) . Methods 36 cases of CT patient in formation stage were taken as therapy group and 25 cases of normal adult as control group. The FPA and DD concentration with ECDSA methods were detected in acute stage, sub acute stage and chronic stage. The results were analyzed statistically. Results The plasma FPA in varied stage of therapy group was higher than that in control group and without significance between stages. DD concentration in therapy group was higher than that in control group. Conclusion The HMM in blood detection could have certain practice value in clinic to diagnose the cerebral thrombosis.
Keywords:Neurology  HMM  FPA  DD Cerebral thrombosis
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