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| 瑞舒伐他汀对兔动脉粥样硬化的影响 | |
| 引用本文： | 张蕊,聂玲,曹国荣,辛辉. 瑞舒伐他汀对兔动脉粥样硬化的影响[J]. 齐鲁医学杂志, 2011, 26(4): 344-346 |
| 作者姓名： | 张蕊 聂玲 曹国荣 辛辉 |
| 作者单位： | 1. 青岛大学医学院附属医院,心内科,山东青岛266003 2. 青岛大学医学院附属医院,心电诊断科,山东青岛266003 |
| 摘 要： | 目的 观察瑞舒伐他汀对兔动脉粥样硬化的影响.方法 新西兰大白兔30只,随机分为对照组、模型组与治疗组,每组10只.对照组以标准基础饲料喂养.模型组和治疗组以高脂饲料喂养4周后,行颈动脉内膜球囊损伤术,分别继续给予高脂饲料及高脂饲料加瑞舒伐他汀喂养6周.于4、10周末取血测定血脂及脂蛋白相关磷脂酶A2(Lp-PLA2)的... |
| 关 键 词： | 动脉粥样硬化 磷脂酶A 瑞舒伐他汀 |
EFFECT OF ROSUVASTATIN ON RABBIT ATHEROSCLEROSIS |
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| ZHANG RUI,NIE LING,CAO GUO-RONG,XIN HUI. EFFECT OF ROSUVASTATIN ON RABBIT ATHEROSCLEROSIS[J]. Medical Journal of Qilu, 2011, 26(4): 344-346 | |
| Authors: | ZHANG RUI NIE LING CAO GUO-RONG XIN HUI |
| Affiliation: | ZHANG RUI,NIE LING,CAO GUO-RONG,XIN HUI(Department of Cardiology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China) |
| Abstract: | Objective To observe the influence of rosuvastatin on atherosclerosis in rabbits. Methods Thirty New Zealand rabbits were equally randomized to control group,model group,and treatment group.Animals in the control group were fed with normal forage,those in the other two groups with high-fat forage for four weeks,and then,endarterium of carotid was injured by balloon,the rabbits were continuously fed with high-fat forage and high-fat plus rosuvastatin,respectively,for six weeks.Blood lipid and Lp-PLA2 were de... |
| Keywords: | atherosclerosis phospholipase A rosuvastatin |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |