A mitochondrial group-I intron in fission yeast encodes a maturase and is mobile in crosses |
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Authors: | Bernd Schäfer Birgit Wilde Domenica Rita Massardo Filomena Manna Luigi Del Giudice Klaus Wolf |
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Affiliation: | (1) Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule, Worringer Weg, D-52056 Aachen, Germany;(2) Istituto Internationale di Genetica e Biofisica, CNR, Via Guglielmo Marconi 10, I-80125 Napoli, Italy |
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Abstract: | The open reading frame in the first intron of the mitochondrial gene encoding subunit I of cytochrome c oxidase encodes a maturase and stimulates homologous recombination in Escherichia coli. In this paper, we demonstrate that this intron is mobile in crosses, indicating that it also encodes an endonuclease. This is the first report on an intron which possesses mobility and acts as a maturase. |
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Keywords: | Schizosaccharomyces pombe Group-I intron Endonuclease Maturase Intron homing |
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