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| 输血对食管癌病人免疫功能的影响 | |
| 引用本文： | 陈克能,徐光炜,师晓天,梅强,周福有,程邦昌. 输血对食管癌病人免疫功能的影响[J]. 中华胸心血管外科杂志, 2001, 17(2): 79-81 |
| 作者姓名： | 陈克能 徐光炜 师晓天 梅强 周福有 程邦昌 |
| 作者单位： | 1. 北京大学临床肿瘤学院暨北京肿瘤医院 2. 河南省安阳市肿瘤医院 3. 武汉大学第一附属医院 |
| 基金项目： | 河南省科技攻关项目、受中国博士后专项基金及北京市科技新星计划资助 |
| 摘 要： | 目的 探讨输血对食管癌病人免疫功能的影响。方法 95例食管癌病人围术期输血者49例、未输血者46例，于术前、术后1、3、7、14?d分别检查细胞及体液免疫指标--外周血T淋巴细胞及其亚群和血浆TNF、红细胞C |
| 关 键 词： | 食管肿瘤 输血 免疫细胞 抗体生成 免疫功能 |
| 修稿时间： | 2000-07-13 |
The effect of blood transfusion during esophagectomy on immune function for patient with esophageal carcinoma |
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| CHEN Keneng,XHI Xiaotian,MEI Qiang,et al.. The effect of blood transfusion during esophagectomy on immune function for patient with esophageal carcinoma[J]. Chinese Journal of Thoracic and Cardiovascular Surgery, 2001, 17(2): 79-81 | |
| Authors: | CHEN Keneng XHI Xiaotian MEI Qiang et al. |
| Affiliation: | CHEN Keneng,XHI Xiaotian,MEI Qiang,et al. Department of Thoracic,Peking University School of Oncology and Beijing Cancer Hospital,Beijing 100036,China. |
| Abstract: | Objective: Blood transfusion can increase the incidence of postoperative infectious complications, and promote cancer growth and metastasis due to its immune suppression. We evaluated the effects of blood transfusion, during esophagectomy of immune function in the patients with esophageal carcinoma. Methods: The study consisted of 95 patients with esophageal carcinoma, all patients underwent esophagectomy. The patients were divided into blood transfusion group (n=49) and non blood transfusion group (n=46) . The immune function test was formed before operation, immediately after anesthesia, on 1st, 2nd, 7th and 14th day after operation . Results: The immune function indexes was lower in blood transfusion group than that in non transfusion group. The incidence of postoperative infectious complication was different in these two groups. Conclusion: Esophagectomy could be performed without blood transfusion. Blood transfusion may aggravate the immune suppression in the patient with esophageal carcinoma after esophagectomy . |
| Keywords: | Esophageal neoplasms Blood transfusion Cellular immunity Antibody Formation |
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