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卡介苗膀胱灌注的并发症及其防治:附9例报告
引用本文:周四维 杨为民. 卡介苗膀胱灌注的并发症及其防治:附9例报告[J]. 临床泌尿外科杂志, 1996, 11(1): 3-5
作者姓名:周四维 杨为民
作者单位:武汉同济医科大学附属同济医院泌尿外科
摘    要:
报告卡介苗(BCG)膀胱内灌注治疗及预防浅表性膀胱肿瘤时的并发症9例。9例患者灌注早期均合并严重膀胱刺激症状,其中高热2例,高热合并膀胱大出血2例,多段尿道狭窄2例,尿道及膀胱肉芽肿并出血3例。并就其发生的原因、预防及治疗进行了讨论。认为发生毒副反应及并发症的原因有局部炎症及过敏反应、BCG进入血循环、BCG膀胱外接种、BCG用量过大等;其预防和治疗措施有中止应用BCG、废止尿道外口直接加压灌注方

关 键 词:卡介苗 膀胱灌注 并发症 防治 膀胱肿瘤

The complications of intravesical perfusion with BCG for treating superficial bladder tumer(Report of 9 cases)
Zhou Siwei,Yang Weimin,Ye Zhangqun,et al. The complications of intravesical perfusion with BCG for treating superficial bladder tumer(Report of 9 cases)[J]. Journal of Clinical Urology, 1996, 11(1): 3-5
Authors:Zhou Siwei  Yang Weimin  Ye Zhangqun  et al
Abstract:
We report the complications in 9 paitents received intravesical perfusion with BCG for treating and preventing superficial bladder tumor.All paitents had severe bladderirritable symptom in initial perfusion.Moreover,2 cases were high fever,2 cases were high fever concomitant severe bleeding in bladder,2 cases were multiple segment urethral stricture,3 cases were granuloma with bleeding in urethral tract and bladder.The following factors were considered to be responsible for the side effects and complications of intravesical BCG therapy:local inflammation and allergic reaction,previous inoculation,and BCG doses used.Measures should be taken to prevent these side effects including diminishing doses of BCG,instilling BCG through an indwelling catheter,not directly through the urethra,enthancing anti-tuberculosis treatment and even suspending BCG administration.
Keywords:BCG intravesical perfusion Complication Prevention  
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