| Halitosis in patients with Helicobacter pylori-positive non-ulcer dyspepsia: an indication for eradication therapy? |
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| 引用本文： | Serin E,Gumurdulu Y,Kayaselcuk F,Ozer B,Yilmaz U,Boyacioglu S. Halitosis in patients with Helicobacter pylori-positive non-ulcer dyspepsia: an indication for eradication therapy?[J]. European Journal of Internal Medicine, 2003, 14(1): 45-48. DOI: 10.1016/S0953-6205(02)00206-6 |
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| 作者姓名： | Serin E Gumurdulu Y Kayaselcuk F Ozer B Yilmaz U Boyacioglu S |
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| 摘 要： |
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| 收稿时间： | 2002-04-22 |
Halitosis in patients with Helicobacter pylori-positive non-ulcer dyspepsia: an indication for eradication therapy? |
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| Serin Ender,Gumurdulu Yuksel,Kayaselcuk Fazilet,Ozer Birol,Yilmaz Ugur,Boyacioglu Sedat. Halitosis in patients with Helicobacter pylori-positive non-ulcer dyspepsia: an indication for eradication therapy?[J]. European Journal of Internal Medicine, 2003, 14(1): 45-48. DOI: 10.1016/S0953-6205(02)00206-6 |
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| Authors: | Serin Ender Gumurdulu Yuksel Kayaselcuk Fazilet Ozer Birol Yilmaz Ugur Boyacioglu Sedat |
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| Affiliation: | 1. School of Gerontology Health Management & Master Program in Long-term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan;2. Taipei City Psychiatric Center, Taipei City Hospital, Taipei, Taiwan;3. Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan;4. Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan;5. College of Medicine, Fu Jen Catholic University, Taipei, Taiwan;6. Institue of Public Health, School of Medicine, National Yang-Ming University, Taipei, Taiwan;7. Department of Psychiatry, School of Medicine, National Yang-Ming University, Taipei, Taiwan |
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| Abstract: | BACKGROUND: The aims of this study were to investigate the frequency of halitosis before and after eradication therapy and to determine whether halitosis is a valid indication for eradication therapy in patients with Helicobacter pylori (H. pylori)-positive non-ulcer dyspepsia. METHODS: Dyspepsia, related symptoms, and halitosis were investigated by way of a questionnaire. Only H. pylori-positive patients who showed no organic lesions on endoscopic examination and no atrophy histopathologically were included. A total of 148 patients fulfilled the above criteria and completed the study. Four weeks after the end of eradication treatment, the symptoms were re-evaluated and repeat endoscopy was done to check for H. pylori in the gastric mucosa. Results: H. pylori eradication was successful in 109 patients (73.6%). Prior to treatment, bloating was the most frequent symptom (74.3%), followed by diurnal pain (62.2%) and halitosis (61.5%). The most successfully resolved symptoms in the group as a whole, regardless of eradication status, were halitosis, diurnal pain, and hunger-like pain, respectively. In the patients with confirmed H. pylori eradication, the most successfully resolved symptoms were halitosis and hunger-like pain, respectively. CONCLUSION: Halitosis is a frequent, but treatable, symptom of H. pylori-positive non-ulcer dyspepsia and may be a valid indication for eradication therapy. |
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