| HPLC测定脂肝清胶囊中栀子苷的含量 |
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| 引用本文： | 原红霞,裴妙荣,裴香萍,段秀俊. HPLC测定脂肝清胶囊中栀子苷的含量[J]. 中国中医药信息杂志, 2011, 18(8): 51+112-51,112. DOI: 10.3969/j.issn.1005-5304.2011.08.020 |
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| 作者姓名： | 原红霞 裴妙荣 裴香萍 段秀俊 |
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| 作者单位： | 山西中医学院,山西太原,030024 |
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| 摘 要： | 目的建立脂肝清胶囊中栀子苷的HPLC测定方法。方法色谱柱为Hypersil BDS-C18柱（4.6 mm×200 mm,5μm）,流动相为乙腈-水（14∶86）,流速为1.0 mL/min,检测波长为240 nm。结果栀子苷进样量在0.139～0.834μg范围内与色谱峰面积之间线性关系良好（r=0.999 5）,平均回收率为101.1%,RSD=2.4%（n=6）。结论本方法简便、快速、准确,可作为脂肝清胶囊的质量控制方法。
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| 关 键 词： | 脂肝清胶囊 栀子苷 高效液相色谱法 含量测定 |
Determination of Geniposide in Zhiganqing Capsules by HPLC |
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| YUAN Hong-xia,PEI Miao-rong,PEI Xiang-ping,DUAN Xiu-jun. Determination of Geniposide in Zhiganqing Capsules by HPLC[J]. Chinese Journal of Information on Traditional Chinese Medicine, 2011, 18(8): 51+112-51,112. DOI: 10.3969/j.issn.1005-5304.2011.08.020 |
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| Authors: | YUAN Hong-xia PEI Miao-rong PEI Xiang-ping DUAN Xiu-jun |
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| Affiliation: | YUAN Hong-xia,PEI Miao-rong,PEI Xiang-ping,DUAN Xiu-jun(Shanxi College of TCM,Taiyuan 030024,China) |
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| Abstract: | Objective To establish a method for determination of geniposide in Zhiganqing Capsules by HPLC.Methods The separation was performed on a Hypersil BDS-C18（4.6 mm×200 mm,5 μm）,with acetonitrile-wate（14∶86） as mobile phase,and the flow rate was 1.0 mL/min.The detection wavelength was set at 240 nm.Results There was good linear relationship between the mass and the peak area of geniposide in the range of 0.139-0.834 ？g（r=0.999 5）.The average recovery was 101.1%,and RSD was 2.4%（n=6）.Conclusion The established method is rapid,simple,accurate and suitable for the quality control of Zhiganqing Capsules. |
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| Keywords: | Zhiganqing Capsules geniposide HPLC content determination |
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