直出1470nm半导体激光膀胱肿瘤剜除术治疗膀胱癌的疗效及安全性研究

目的 探讨应用直出1470nm半导体激光行经尿道膀胱肿瘤剜除术治疗非肌层浸润性膀胱癌(non-muscle invasive bladder cancer,NMIBC)的疗效和安全性.方法 回顾性的分析2014年6月至2014年12月在本院,应用直出1470nm半导体激光行经尿道膀胱肿瘤剜除术且术后病理证实为非肌层浸润性膀胱癌的30例患者.收集患者的手术时间、术中出血量、术中术后并发症、留置尿管时间和住院时间等临床资料.并收集所有患者术后随访资料.结果 所有患者均顺利完成手术,未发生膀胱穿孔等重并发症.平均手术时间(22.5±7.5) min,平均术中出血量(12.5±2.5)mL.平均术后膀胱冲洗时间(2±1)d,平均留置尿管时间(3.5±1.5)d,平均术后住院时间(4±2)d.术后随访12 ～ 18个月,肿瘤复发率为16.70％.结论 应用直出1470nm半导体激光行经尿道膀胱肿瘤剜除术是一种安全、有效的治疗NMIBC的手术方式.

Effect of Front-firing 1470 nm diode laser enucleation in the treatment of non-muscle invasive bladder tumor

Objectives To explore the safety and efficacy of front-firing 1470 nm diode laser enucleation in the treatment of non-muscle invasive bladder tumor (NMIBC).Methods Clinical data of 30 patients with NMIBC who treated with front-firing 1 470 nm diode laser enucleation in our hospital from June 2014 to December 2014 were reviewed.Operation time,hemorrhage volume during surgery,operation complications,indwelling catherization time,hospital stay time and recurrence incidence were analyzed.Results All operations were completed successfully without severe complications.The average operating time was (22.5 ± 7.5) min,and hemorrhage volume during surgery was (12.5 ± 2.5)mL.The average indwelling catherization time and hospital stay time was (3.5 ± 1.5)d,(4 ±2)d,respectively.Following up of 12 ～ 18 months postoperative,the recurrence rate was 16.7％.Conclusions Front-firing 1470 nm diode laser enucleation is a safe and effective operation method for the NMIBT.