长链非编码RNA在卵巢癌中的研究进展

长链非编码RNA (lncRNA)是指长度超过200个核苷酸、具有调控基因表达作用的非编码RNA,近年来,因其具有复杂的生物学功能而引起了研究者的广泛关注.目前研究证实,lncRNA与多种肿瘤的发生发展有着密切的关系,可能参与促进或抑制肿瘤的生长和与肿瘤的转移有关.在卵巢癌中,某些lncRNA也被证实可能参与其致病过程.

The research development of lnc RNA in ovarian cancer

Long non-coding RNA (lncRNA) is a class of non-coding RNA with the length of more than 200 nucleotide which,regulates the expression of gene.In recent years,researchers have paid more attention to the lncRNA because of its complicated biological function.Present studies have confirmed that the tumor's occurrence and development have a close relationship with lncRNA.In the ovarian cancer,the expression level of specific clusters of lncRNA changes significandy,which provides important basis to the new targeted treatment of ovarian cancer and more powerful guide to the clinical work.