同型半胱氨酸、胱抑素C和超敏C反应蛋白在动脉粥样硬化中的临床意义

目的探讨动脉粥样硬化(AS)患者血清同型半胱氨酸(Hcy)、胱抑素C(Cys C)和超敏C反应蛋白(hs-CRP)的临床价值。方法选择100例初诊AS患者作为观察组,36例治疗后病情明显好转的AS患者作为治疗组,120例健康体检人群作为健康对照组,检测所有研究对象的血清Hcy、Cys C和hs-CRP并进行结果比较。结果观察组患者血清Hcy、Cys C和hs-CRP水平与健康对照组比较,明显升高,差异有统计学意义(P0.05);治疗组患者Cys C和hs-CRP水平明显低于观察组,差异有统计学意义(P0.05)。结论监测血清Hcy、Cys C和hs-CRP水平对AS的诊断、治疗效果评价和预后判断具有一定的临床价值。

The value of cystatin C,homocysteine and super-sensitivity C-reactive protein in the atherosclerosis

Objective To investigate the clinical value of homocysteine (Hcy) ,cystatin C (Cys C) and high‐sensitivity C‐reactive protein (hs‐CRP) in atherosclerosis (AS) .Methods Totally 100 cases of newly diagnosed patients of AS were choosed as the ob‐servation group ,36 cases condition improved markedly of AS after treatment as the treatment group ,and 120 cases of normal medi‐cal groups as the control group ,the Hcy ,Cys C and hs‐CRP in all subjects were detected respectively .Results Hcy ,Cys C and hs‐CRP levels of observation group were significantly higher than those of normal groups ,and the difference was statistically signifi‐cant (P< 0 .05) .While the Cys C and hs‐CRP levels of treatment group were significantly lower than the those of observation group ,the difference was also statistically significant (P< 0 .05) .Conclusion The detection of Serum Hcy ,Cys C and hs‐CRP might be help to the diagnosis ,treatment evaluation and prognosis of AS .