Prognostic significance of the number of lymph nodes in elective neck dissection for tongue and mouth floor cancers |
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| Authors: | Ali Amar Helma Maria Chedid Abrão Rapoport Claudio Roberto Cernea Rogério Aparecido Dedivitis Otávio Alberto Curioni Lenine Garcia Brandão |
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| Affiliation: | 1. PhD in Medicine – Graduate Program in Otorhinolaryngology and Head and Neck Surgery – Federal University of São Paulo (UNIFESP). Surgeon at the Otorhinolaryngology and Head and Neck Surgery Department – Heliópolis Hospital, São Paulo – SP;2. MSc in Sciences – Heliópolis Hospital, São Paulo, SP. Surgeon at the Otorhinolaryngology and Head and Neck Surgery Department – Heliópolis Hospital, São Paulo – S P;3. Senior Associate Professor – Department of Surgery – Medical School of the University of São Paulo – USP, São Paulo, SP. Surgeon at the Otorhinolaryngology and Head and Neck Surgery Department – Heliópolis Hospital, São Paulo – S P;4. Associate Professor – Department of Head and Neck Surgery – Medical School of the University of São Paulo USP, São Paulo, SP;5. MD. Senior Associate Professor – FundaçãoLusíada – UNILUS;6. PhD in Medicine – Graduate Program in Pathology – Medical School of the University of São Paulo. Head of the Department of Head and Neck Surgery – Heliópolis Hospital, São Paulo –SP);7. Full Professor – Department of Head and Neck Surgery – Medical School of the University of São Paulo – USP, São Paulo, SP. Departamentos de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia do Hospital Heliópolis e de Cirurgia de Cabeça e Pescoço da Faculdade de Medicina da USP, São Paulo/SP |
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| Abstract: | ![]()
The presence of metastatic lymph nodes is a relevant aspect in the treatment of head and neck cancer, bringing about a 50% reduction in survival.ObjectiveTo assess the number of lymph nodes removed in the neck dissection and their relationship with the prognosis.MethodsA retrospective study involving 143 patients with tongue and mouth floor epidermoid carcinoma, which histological exam showed no lymph node metastases. Among those, 119 were males and 24 females, with mean age of 54 years. As to the primary tumor site, 65 were in the tongue and 78 in the mouth floor. T stage distribution was of four T1, 84 T2, 36 T3 and 19 T4. We carried out 176 neck dissections, unilateral in 110 cases and bilateral in 33. Of these, 78 were radical and 98 selective. The patients were broken down into three groups, according to the 33 and 66 percentiles of the number of lymph nodes resected.ResultsThe mean number of resected lymph nodes was 27; 24 in selective dissections and 31 in the complete ones. We did not have statistically significant differences when associated to the T and N stages.ConclusionsThe larger number of lymph nodes dissected in the neck dissection identifies the group of better prognoses among pN0 cases. |
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| Keywords: | carcinoma squamous cells lymph nodes mouth neoplasms neck dissection |
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