基底动脉尖综合征临床及影像学分析

目的探讨基底动脉尖综合征（TOBS）的临床与影像学特征。方法对2005年3月至2007年3月32例TOBS患者的临床资料进行回顾性分析。结果TOBS的临床主要表现为一过性意识障碍、眩晕、眼球运动障碍及瞳孔的变化、肢体运动障碍、偏盲或皮质盲、共济失调及记忆功能损害；磁共振（MRI）显示梗死灶在丘脑、小脑、中脑、脑桥、枕叶、颞叶内侧面；数字减影血管造影（DSA）显示为基底动脉及椎动脉闭塞或狭窄。结论临床表现和MRI表现是诊断TOBS的主要依据，DSA能为病变提供血管定位依据，对治疗及预防TOBS有指导性意义。

Clinical and imaging analysis of top of the basilar artery syndrome

Objective To explore the clinical manifestation of top of the basilar artery syndrome(TOBS)and its imaging features.Methods The clinical data of 32 patients with TOBS admitted from March 2005 to March 2007 were retrospectively analyzed.Results The clinical manifestations of TOBS comprised transient unconsciousness,vertigo,dyskinesia of eyeball,abnormality of pupils,dyskinesia of limbs,hemianopsia or cortical blindness,ataxia and memory impairment.MRI showed the local infarction in thalami,cerebellum,midbrain,pons,occipital lobe,temporal inner surface.The features of DSA were occlusion or stenosis in basilar artery and vertebral artery.Conclusions The clinical manifestation and MRI features are the main basis in diagnosis of TOBS,and DSA application can offer the possible localization of vascular lesion and instruct treatment and prevention for TOBS.