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| 高通量分析技术在肿瘤MDR中的研究进展 | |
| 引用本文： | 周铭,梁钢. 高通量分析技术在肿瘤MDR中的研究进展[J]. 国外医学(肿瘤学分册), 2006, 0(12) |
| 作者姓名： | 周铭 梁钢 |
| 作者单位： | 广西医科大学药学院药理教研室，广西医科大学药学院药理教研室 |
| 基金项目： | 广西壮族自治区科技厅自然科学基金(0447043) |
| 摘 要： | 高通量分析技术是近年来肿瘤研究新平台,肿瘤多药耐药(MDR)和耐药逆转药物研究在肿瘤化疗领域亟需解决。现综述基因芯片、蛋白质芯片、组织芯片三大高通量微阵列技术在肿瘤MDR机制、筛选耐药逆转靶点和逆转药物及指导临床个体化治疗等方面的应用。 |
| 关 键 词： | 微阵列分析 肿瘤 抗药性 抗肿瘤药 |
Research advancement of high-throughput analysis technology in tumor multidrug resistance and resistance reversal agent |
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| ZHOU Ming LIANG Gang. Research advancement of high-throughput analysis technology in tumor multidrug resistance and resistance reversal agent[J]. Foreign Medical Sciences (Cancer Section), 2006, 0(12) | |
| Authors: | ZHOU Ming LIANG Gang |
| Affiliation: | ZHOU Ming LIANG Gang.Department of Pharmacology,College of Pharmacy,Guangxi Medical University,Nanning 530021,China |
| Abstract: | In recent years,high-throughput analysis technology has become one of the new princi- pal platform technologies for tumor research.It is urgent that tumors multidrug resistance and resistance re- versal agent should he resolved in chemotherapy domain.This review aims to present the research ad- vancement of three high-throughput microarray techniques,including gene chip,protein chip and tissue chip,their application in the mechanisms of tumor multidrug resistance,and to summarize the latest devel- opments of screening resistance reversal targets and new agent.The success of microarray technology will provide guidance for clinical individualized cancer treatment. |
| Keywords: | Microarray analysis Neoplasms Drug resistance Antineoplastic agents |
| 本文献已被 CNKI 等数据库收录！ | |