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不同穴位电针治疗卡那霉素中毒性听力损害的实验研究
引用本文:孙德利 宋如垓. 不同穴位电针治疗卡那霉素中毒性听力损害的实验研究[J]. 针刺研究, 1995, 20(3): 62-66
作者姓名:孙德利 宋如垓
作者单位:浙江中医学院!杭州310009(孙德利,刘元亮,方剑乔,金小明),复旦大学生理学和生物物理学系!上海200433(宋如垓)
摘    要:
本实验采用形态与机能相结合的技术和方法,观察了不同穴位在电针治疗卡那霉素中毒性听力损害中的效应·以筛选针灸治聋的有效穴位。结果表明:听宫、翳风、外关、肾俞、三阴交、筑宾等穴为针灸治疗药物中毒性听力损害的有效穴位,尤以听宫、三阴交、筑宾等穴位用效果更佳。局部穴位听宫与翳风效应比较无显著性差异。电针疗法能提高听力.改善SDH活性,缓解药物对听毛细胞进行性损害的程度。指出FFR在药物耳毒性作用检测中具有重要意义。

关 键 词:穴位特异性  听力丧失  针灸疗法  琥珀酸脱氢酶  频率跟随反应

Treatment of Ototoxic Auditory Damage Caused by Kanamycin with Electroacupuncture at Different Acupoints
Abstract:
We adopted the technitlue and rnethod of integrating the morphology with function to select theeffective aeupoints for treatrnent of deafness.The results show that: (1 ) Tinggong (SI 19 ) - Ylfeng (TE 17 ), Waiguan (TE 5 ), Shenshu(UB 23 ) - Sany1njiao (SP 6 ) and Zhubin (KI 9 ) etc. are the effectine acupoints for the treatment of ototoxlc auditory damage caused by drug. especially. the effect of Tinggong, Sanyinjiao and Zhubinetc, is much better: (2) electroacupuncture can promote audibility, improve SDH activity and relieveprogressing injury of auditory hair cells, (3) FFR mithod has an important significance in the determinaation of ototoxic damage caused by drug
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