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37例胃肠道间质瘤预后因素分析
引用本文:王悦冬,邓国明,周臻涛,张开鄂,李旭刚. 37例胃肠道间质瘤预后因素分析[J]. 肿瘤基础与临床, 2011, 24(2): 143-146
作者姓名:王悦冬  邓国明  周臻涛  张开鄂  李旭刚
作者单位:梅州市人民医院肿瘤外一科,广东,梅州,514031
摘    要:
目的 探讨影响胃肠道间质瘤(GIST)预后的因素.方法 回顾性分析37例GIST患者的免疫组化检测结果 及肿瘤大小、生长部位、核分裂数,手术的切除程度与其预后的关系.结果 GIST患者的病理切片中CD117、CD34的阳性表达率分别为97.3%和78.4%.肿瘤直径>10 cm、5~10 cm者预后较≤5 cm者差(P...

关 键 词:胃肠间质瘤  预后  临床分析

The Clinical Analyses of the Prognosis Factors of 37 Patients with Gastrointestinal Stromal Tumor
Wang Yuedong,Deng Guoming,Zhou Zhentao,Zhang Kaie,Li Xugang. The Clinical Analyses of the Prognosis Factors of 37 Patients with Gastrointestinal Stromal Tumor[J]. Journal of Basic and Clinical Oncology, 2011, 24(2): 143-146
Authors:Wang Yuedong  Deng Guoming  Zhou Zhentao  Zhang Kaie  Li Xugang
Affiliation:(The First Department of Surgical Oncology,Meizhou People′s Hospital,Meizhou 514031,China)
Abstract:
Objective To investigate the prognostic factors of patients with gastrointestinal stromal tumor(GIST).Methods The clinical data of 37 patients with GIST were reviewed retrospectively.The clinicopathologic diagnoses were determined by immunochemistry method.The relationships of the prognoses with tumor size,tumor location,mitotic counts and range of tumor resection were analyzed.Results The positive rates of CD117 and CD34 were 97.3% and 78.4% in the pathological sections of patients with GIST respectively.The patients with tumor size >10 cm and 5-10 cm,mitotic counts >5/50 HPF,incomplete resection had poorer outcome than those of tumor size ≤5 cm,mitotic counts ≤5/50 HPF,complete resection(P<0.05).Conclusion Complete resection can improve the prognosis of patients with GIST.Tumor size and tumor mitotic counts are the prognostic factors.
Keywords:gastrointestinal stromal tumor  prognosis  clinical analysis
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