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Trypanocidal activity of chemical constituents from Lychnophora salicifolia Mart |
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| Authors: | Jordão Christiane Oliveira Vichnewski Walter de Souza Glória Emília Petto Albuquerque Sérgio Lopes João Luis Callegari |
| Affiliation: | Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeir?o Preto, Ribeirao Preto, SP, Brazil. |
| Abstract: | The ethyl acetate extract from leaves plus inflorescences of L. salicifolia showed significant trypanocidal activity against trypomastigote forms of T. cruzi, which was due to the flavonoid quercetin-7,3',4'-trimethyl ether and the sesquiterpenoid lychnopholic acid. Despite the use of some species of Lychnophora in folk medicine for pain relief, crude extracts from L. salicifolia Mart. showed no antinociceptive activity in the mouse writhing test. |
| Keywords: | Lychnophora salicifolia flavonoids sesquiterpenoids writhing test trypanocidal activity |
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