良性阵发性位置性眩晕与前庭性偏头痛患者焦虑抑郁状态比较研究

目的 比较良性阵发性位置性眩晕（benign paroxysmal positional vertigo，BPPV）患者和前庭性偏头痛 （vestibular migraine，VM）患者焦虑、抑郁的发生率和特点。 方法 收集2016年9月-2017年9月诊断为BPPV和VM患者各50例。对两组患者进行眩晕残障量表 （dizziness handicap inventory，DHI）和医院焦虑抑郁量表（hospital anxiety and depression scale，HADS）评 定，比较两组基线资料和DHI 、HADS评分的差异。 结果 治疗前BPPV组存在明显眩晕残障者32例（64%），存在焦虑抑郁者15例（30%），治疗后分 别为3例（6%）和2例（4%），差异有统计学意义（P＜0.001和P =0.001）；治疗前VM组存在明显眩晕 残障者38例（76%），存在焦虑抑郁者为28例（56%），治疗后分别为12例（24%）和8例（16%），差异 均有统计学意义（均P＜0.001）。治疗前VM组DHI55.00（44.00～70.00）vs 31.00（20.00～45.00），P ＜0.001]和HADS评分13.50（6.00～20.00）vs 6.00（3.75～10.00），P =0.001]高于BPPV组，其中DHI评 分中情感、躯体和功能3个分项的评分也均高于BPPV组，差异均有统计学意义。治疗后VM组DHI22.00 （12.00～34.00）vs 0（0～4.00），P＜0.001]和HADS评分7.50（2.00～10.50）vs 0（0～3.00），P＜0.001] 仍高于BPPV组，其中DHI评分中情感、躯体和功能3个分项的评分也均高于BPPV组，差异均有统计学 意义。 结论 VM患者焦虑抑郁严重程度高于BPPV患者，两组经治疗后焦虑抑郁的发生率均有显著下降。

Comparison of Anxiety and Depression between Patients with Benign Paroxysmal Positional Vertigo and Vestibular Migraine

Objective To compare the incidence and charateristics of anxiety and depression between the
patients with benign paroxysmal positional vertigo (BPPV) and vestibular migraine (VM).
Methods 100 outpatients diagnosed with BPPV (n =50) and VM (n =50) at Beijing Tian Tan
Hospital from September 2016 to December 2017 were included in the analysis. Dizziness handicap
inventory (DHI) and hospital anxiety and depression scale (HADS) were used to evaluate the
emotional state of the two groups.
Results In BPPV group: the incidence of significant dizziness handicap, depression and anxiety
were 64% (32/50) and 30% (15/50) before treatment respectively, and reduced to 6% (3/50) and
4% (2/50) after treatment respectively, and the differences before and after treatment had statistical
significance (P <0.001 and P =0.001, respectively). In VM group: the incidence of significant
dizziness handicap, depression and anxiety were 76% (38/50) and 56% (28/50) before treatment
respectively, and reduced to 24% (12/50) and 16% (8/50) respectively, and the differences before
and after treatment had statistical significance (P <0.001 and P <0.001, respectively). Beforetreatment, the DHI 55.00 (44.00-70.00) vs 31.00 (20.00-45.00), P <0.001] and HADS scores 13.50
(6.00-20.00) vs 6.00 (3.75-10.00), P =0.001] were both higher in VM group than that in BPPV
group and what’s more, the scores in functional, emotional and physical items were all significantly
higher in VM group than that in BPPV group. After treatment, the scores of DHI 22.00 (12.00-34.00)
vs 0 (0-4.00), P <0.001] and HADS scores 7.50 (2.00-10.50) vs 0 (0-3.00), P <0.001] in VM group
were still higher than that in BPPV group, and similarly, the scores in functional, emotional and
physical items were all higher in VM group than that in BPPV group, and the above differences all
had statistical significance.
Conclusions The incidence and severity of anxiety and depression were both higher in VM
patients than that in BPPV patients, and the incidence greatly declined in VM and BPPV patients
after treatment.