慢性阻塞性肺疾病患者运动能力与生活质量的相关性研究

目的:探讨慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者运动能力、生活质量现状及相关性。方法:2018年9月至2019年5月对复旦大学附属中山医院154例COPD患者进行横断面调查,采用6 min行走距离(six-minute walk distance,6 MWD)评估患者运动能力,使用一般资料调查表、圣·乔治呼吸问卷(SGRQ)进行调查分析。结果:患者6 MWD为(379.65±121.05)m; SGRQ问卷得分为(42.12±17.54)分;6 MWD与SGRQ得分负相关,差异有统计学意义(r=-0.422,P0.001);患者的年龄、体质量指数(BMI)、吸烟指数、疾病严重程度和6 MWD对生活质量(SGRQ得分)有影响;6 MWD、高龄、吸烟指数和BMI是患者生活质量水平的影响因素。结论:COPD患者生活质量、运动能力处于较低水平。生活质量与运动能力、年龄、BMI等显著相关。

Correlation between exercise capacity and quality of life in patients with chronic obstructive pulmonary

Objective: To evaluate the status of exercise capacity and quality of life in patients with chronic obstructive pulmonary disease and analyze their correlations, in order to provide intervention basis for improving the quality of life of patients with chronic obstructive pulmonary disease. Methods: A cross-sectional survey was used to investigate 154 outpatients with COPD. The 6-minute walking test was used to evaluate the exercise ability of the patients. The general data questionnaire and St. George''s breathing questionnaire (SGRQ) were used to conduct the survey. SPSS 22.0 software was used for statistical analysis. Results: The 6MWD distance of the patients was 379.65±121.05 m; the quality of life (SGRQ) questionnaire score was 42.12±17.54 points; there was a negative correlation between the 6MWD and SGRQ scores, and the difference was statistically significant (r = -0.422, P <0.001); Univariate analysis showed that age, BMI, smoking index, disease severity and 6MWD were statistically significant; The results of multiple linear regression analysis showed that 6MWD, advanced age, smoking index and BMI were influencing factors of patients'' quality of life, which explained 31.60% of the total variation. Conclusion: The quality of life of patients with COPD is generally at a low level and their exercise capacity is at a low level. Quality of life was significantly related to exercise capacity, age, and BMI. Health care workers should pay attention to the factors affecting the quality of life of patients, strengthen exercise interventions, nutrition guidance and health education to improve their quality of life.