合并慢性前列腺炎的慢性肾脏病患者临床病理特点

目的：探讨合并慢性前列腺炎（CP）的男性慢性肾脏病（CKD）患者临床病理特点。方法：比较伴CP与不伴CP的CKD患者的年龄、婚姻情况、蛋白尿、血尿、肾功能水平及病理类型等临床病理指标。结果：（1）合并CP组平均年龄较不伴CP组大[（232.6±12.7）岁vs（9.5±11.4）岁],CP组已婚率高（63.7%vs47.3%）（P均〈0.05）;大量蛋白尿（〉3.5g/24h）52例（57.1%）,CP组中最常见的3种肾脏病为IgA肾病31例（34.1%）,非IgAN系膜增生性肾小球肾炎24例（26.4%）,膜性肾病12例（13.2%）,其中膜性肾病的发生率较不伴CP组（4.4%）高（P〈0.05）;伴CP的IgAN患者血管襻IgA沉积率较不伴CP患者高（P〈0.05）。（3）CP组与不伴CP组在蛋白尿、血尿、肾功能方面比较差异无统计学意义。结论：伴CP的CKD者年龄较大,多为已婚,半数伴大量蛋白尿,具有一定的临床病理特点,CP可能造成某些CKD患者慢性化改变。

Clinicopathological Characteristic in Patients with Chronic Kidney Disease and Chronic Prostatitis

Objective：To study the clinicopathological characteristic in patients with chronic kidney disease（CKD） and chronic prostatitis（CP）.Methods：The examination of Prostatic fluid was performed in 273 male patients with CKD diagnosed by renal biopsy.The age,state of marriage,degree of proteinuria and hematuria and level of serum creatinine and other clinicopathologic data were compared between the CKD patients with CP and those patients without CP.Results：The average age of the CKD patients with CP was higher than that of the patients without CP（P0.05）.63.7% of patients with CP had been married,and only 47.3% of patients CP had not been married. There was significant difference between the two groups.The nephrotic protein（3.5 g/24 h） was found in 52（57.1%） cases with CP.IgAN（34.1%）,no-IgAN mesangial proliferative glomerulonephritis（26.4%）and membranous nephropathy（13.2%）were the most frequent pathologic types in patients with CP.Incidence of membranous nephropathy in patients with CP was higher than that in patients without CP.There was no significant difference in degree of proteinuria and hematuria and level of serum creatinine between the two groups.Conclusion：57.1% of CKD accompanied by CP had nephrotic proteinuria.There might be relationship between CP and CKD.The CKD with CP have some clinicopathologic features.CP may induce chronic changes in renal tissue.