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妊娠期肝内胆汁淤积症与母婴健康的关系
引用本文:许娟,张洪波,张丽英,金敏娟,徐海玉,侯东云. 妊娠期肝内胆汁淤积症与母婴健康的关系[J]. 疾病控制杂志, 2004, 8(1): 25-27
作者姓名:许娟  张洪波  张丽英  金敏娟  徐海玉  侯东云
作者单位:1. 安徽医科大学公共卫生学院儿少卫生与妇幼,保健学系,安徽,合肥,230032
2. 合肥市西市区妇幼保健所,安徽,合肥,230031
基金项目:安徽医科大学校基金资助项目 (2 0 0 2 14 )
摘    要:
目的 探索妊娠期肝内胆汁淤积症(ICP)与孕产妇及其子代健康的关系。方法 对合肥市西市区妇幼保健所一年中2007例孕产妇妊娠期、分娩期和产褥期的健康资料及新生儿的健康状况资料进行分析。结果 该社区IcP发生率为12.31%。ICP组剖宫产率、产后出血率分别为46.96%和6.88%,均高于对照组(34.94%、2.95%),且差异有统计学意义。ICP组胎儿窘迫率为25.51%,高于对照组的16.88%,差异有统计学意义。依据Apgar评分,ICP组和对照组新生儿重度窒息分别为3.OO%、1.19%,差异有统计学意义。结论 ICP不仅增加孕产妇剖宫产和产后出血的危险,而且与胎儿窘迫和新生儿重度窒息相关联。

关 键 词:妊娠期肝内胆汁淤积症 母婴健康 妊娠并发症 分娩结局
文章编号:1008-6013(2004)01-0025-03
修稿时间:2003-05-20

The influence of ICP on maternal and children''''s health
XU Juan ,ZHANG Hong-bo ,ZHANG Li-ying ,JIN Min-juan ,XU Hai-yu ,HOU Dong-yun .. The influence of ICP on maternal and children''''s health[J]. Chinese Journal of Disease Control and Prevention, 2004, 8(1): 25-27
Authors:XU Juan   ZHANG Hong-bo   ZHANG Li-ying   JIN Min-juan   XU Hai-yu   HOU Dong-yun .
Affiliation:XU Juan 1,ZHANG Hong-bo 1,ZHANG Li-ying 1,JIN Min-juan 2,XU Hai-yu 2,HOU Dong-yun 2. 1.Department of Maternal and Child Health School of Public Health,Anhui Medical University,Hefei 230032,China, 2.Institute of Maternal and Health Care of West-district of Hefei,Hefei 230031,China
Abstract:
Objective To determine the relationship of intrahepatic cholestasis of pregnancy (ICP) to maternal and child health. Methods In the study, 2 007 pregnant women were involved. A case-control study was employed to analyze their perinatal data and neonatal data. Results The incidence of ICP was 12.31% in this district. The rates of cesarean and postpartum hemorrhage were 46.96% and 6.88% respectively in ICP group; both were higher than non-ICP group. The rate of fetal distress in ICP group was 25.51%, significantly higher than control group; the rate of asphyxia of newborn was significantly higher than non-ICP group. Conclusions ICP not only increases the risk of cesarean and postpartum hemorrhage but also is related with fetal distress and asphyxia of newborn.
Keywords:pregnancy complications  cholestasis   intrahepatic  perinatology
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