肺气虚证和肺阴虚证患者外周血NK细胞表达分析

目的:观察肺气虚证患者和肺阴虚证患者外周血自然杀伤细胞(NK细胞)表达状况.方法:应用流式细胞仪分别对58例肺气虚证患者、12例肺阴虚证患者和20例健康查体者CD16/CD56进行测定.结果:肺气虚证患者和肺阴虚证患者NK细胞活性下降;肺气虚证各组间NK细胞活性也存在明显的差异.结论:肺气虚证患者免疫功能由早期的活跃状态逐步发展到不同程度的免疫抑制,然后发展至肺阴虚证,最终导致免疫系统内环境稳定失调.

Analysis on Expression of NK Cells in Peripheral Blood in the Patients of Lung-Qi Deficiency and Lung-Yin Deficiency

Objective:To observe expression of NK cells in peripheral blood in the patients of lung-Qi deficiency and lung-Yin deficiency. Methods:CD_(16)/CD_(56) were determined by flow cytometry in 58 cases of lung-Qi deficiency,12 cases of lung-Yin deficiency and 20 cases of healthy persons.Results:Activities of NK cells in both the patient of lung-Qi deficiency and the patient of lung-Yin deficiency decreased;There were significant differences in activities of NK cells among the various groups of lung-Qi deficiency syndrome.Conclusion:The immunological function in the patient of lung-Qi deficiency syndrome developed gradually to immunodepression of different degrees from active state at early stage,and then developed to lung-Yin deficiency syndrome,and finally leading to maladjustment of hemeostasis of immunological system.