2型糖尿病患者胃动力学与植物神经病变关系的探讨

目的研究胃动力障碍及植物神经病变与2型糖尿病(DM2)的关系。方法采用半流质核素胃排空试验对129例DM2患者的胃动力进行了研究，同时还用Ewing法对心血管植物神经功能、用B超对膀胱残余尿量、用神经病星对外周神经进行定量测定。结果糖尿病胃排空延迟发生率为62.02％。植物神经病变呈弥漫性分布，随病程延长而加重。胃动力异常者，其植物神经病变发生率较胃动力正常者显著增高。结论DM2胃动力异常及植物神经病变发生率均明显增高，二者显著相关。故早期进行胃排空试验，并同时对其它植物神经功能进行测定，对糖尿病胃及神经并发症的早期防治有重要意义。

The relationship between gastric motility and autonomic neuropathy in type 2 diabetes

Objective To study the association of gastric motility abnormalities and autonomic neuropathy in type 2 diabetes. Methods Gastric motility of 129 patients with type 2 diabetes were studied by using radionuclide semi liquid gastric emptying test; Cardiovascular autonomic function, amount of residual urine in bladder and peripheral nerve function were also assessed by Ewing method, ultrasonic and neuropathy star, respectively. Results Gastric motility dysfunction was found in 62 02% of diabetic patients. Autonomic neuropathies were distributed diffusely, and became severe with enlonged duration of the disorder. The percentage of neuropathy in patients with gastric motor abnormalities was higher than that in normal gastric motility patients. Conclusion The incidence of normal gastric motor abnormalities and autonomic neuropathy were both increased in type 2 diabetes and both of them were significantly correlated. It is important to study the gastric emptying and other autonomic nerve functions, and to treat these complications in early stage of diabetes.