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| 卡维地洛对高血压患者血浆内皮素、降钙素基因相关肽的影响 | |
| 引用本文： | 韩燕,楼建英,周民伟,王达理,周春蕾,张伟,张必利,王燕. 卡维地洛对高血压患者血浆内皮素、降钙素基因相关肽的影响[J]. 高血压杂志, 2003, 11(5): 427-428 |
| 作者姓名： | 韩燕 楼建英 周民伟 王达理 周春蕾 张伟 张必利 王燕 |
| 作者单位： | 南京解放军第454医院 江苏南京210002(韩燕，楼建英，周民伟，王达理，周春蕾，张伟，张必利)，南京解放军第454医院 江苏南京210002(王燕) |
| 摘 要： | 目的 探讨卡维地洛对高血压患者血压和血浆内皮素 (ET 1)、降钙素基因相关肽 (CGRP)的影响。方法 测定 60例高血压患者用药前后血压、血浆ET 1、CGRP的变化 ,2 5例健康人做为对照组。结果 患者血浆ET -1明显高于正常组 (P <0 0 5) ,CGRP则低于正常组。卡维地洛治疗后血压明显下降 ;血浆ET -1水平降低 ,CGRP水平升高 (P <0 0 5)。结论 卡维地洛可有效控制血压 ,并有降低高血压患者的血浆ET 1,升高血浆CGRP的作用 |
| 关 键 词： | 卡维地洛 高血压 血浆内皮素 降钙素基因相关肽 |
Effect of Carvedilol on Serum ET-1, CGRP in the Hypertensive Patients |
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| HAN Yan,LOU Jian ying,ZHOU Min wei,et al.. Effect of Carvedilol on Serum ET-1, CGRP in the Hypertensive Patients[J]. Chinese Journal of Hypertension, 2003, 11(5): 427-428 | |
| Authors: | HAN Yan LOU Jian ying ZHOU Min wei et al. |
| Abstract: | Objective To study the effect of carvedilol on blood pressure, serum ET 1,CGRP in the patients with hypertension. Method Blood pressure, serum ET 1,CGRP concentration were measured in 60 hypertensive patients before and after carvedilol(5-10 mg Bid) for 3 months. 25 normal persons were served as control group. Results Serum ET 1 were higher and CGRP were lower in hypertensive patients than that in normal persons. After carvedilol treatment blood pressure and serum ET 1 were reduced remarkably,while CGRP concentration was increased. Conclusion Blood pressure was reduced remarkably, serum ET 1 were reduced and CGRP were increased in hypertensive patients after carvedilol treatment. |
| Keywords: | carvedilol hypertension serum ET 1 CGRP |
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