耐甲氧西林金黄色葡萄球菌耐药性分析

目的了解耐甲氧西林金黄色葡萄球菌(MRSA)对各种抗菌药物的耐药性。方法 对30株MRSA进行药敏实验,药敏实验采用VITEK32全自动微生物分析仪GPS药敏板。结果 在测试的14种抗菌药物中,万古霉素未出现耐药菌株,对呋喃妥因、利福平、复方磺胺甲口恶唑耐药率低(分别为6.7%、10.0%、20.0%)。对氯霉素耐药率为53.3%,对克林霉素、红霉素、庆大霉素、四环素、左氧氟沙星耐药率均在90.0%以上。对氨苄西林、头孢唑啉、苯唑西林、青霉素则是全耐药。结论 应加强抗菌药物的合理应用,减少MRSA耐药事件的发生。

Analysis of resistance to drug of methicillin-resistant staphylococcus aureus

Objective To learn about the resistance to drug of methicillin-resistant staphylococcus aureus（MRSA）to various antimicrobial drug.Methods 30 strains of MRSA were maken drug-sensitivity test,by VITEK32 GPS drug susceptibility plate.Results In testing 14 antimicrobial drugs,vancomycin not appeared resistant strains,the resistant rate of nitrofurantoin,rifampicin,sulfamethoxazole were low（6.7%,10.0%,20.0%）.Resistant rate to chloramphenicol was 53.3%,Resistant rate of clindamycin,erythromycin,gentamicin,tetracycline,levofloxacin all were 90.0% or more.To ampicillin,cefazolin,oxacillin,penicillin was the full resistance.Conclusion We will strengthen the rational use of antibiotics to reduce the incidence of MRSA resistance.