| 黄心分散片的处方工艺研究 |
| |
| 引用本文： | 张芳,韩丽,张定堃,杨迎光,唐宜轩,秦春凤.黄心分散片的处方工艺研究[J].辽宁中医杂志,2014(11):2422-2425. |
| |
| 作者姓名： | 张芳 韩丽 张定堃 杨迎光 唐宜轩 秦春凤 |
| |
| 作者单位： | 成都中医药大学中药资源系统研究与开发利用省部共建国家重点实验室培育基地 |
| |
| 基金项目： | 国家自然科学基金面上项目（30973952） |
| |
| 摘 要： | 目的:研究黄心分散片的处方工艺。方法:采用单因素法,以崩解时间为评价指标,筛选黄心分散片的制备工艺,并测定其溶出度。结果:黄心分散片的处方组成为:黄芩苷50%,穿心莲内酯12.5%,MCC22.5%,L-HPC10%,微粉硅胶5%;崩解时间为(75±4)s;黄心分散片中黄芩苷与穿心莲内酯的溶出速度与程度均高于黄心胶囊。结论:该黄心分散片处方合理,工艺可行。
|
| 关 键 词： | 黄心分散片 制备工艺 单因素法 |
Formulation and Technology of Huangxin Dispersible Tablets |
| |
| ZHANG Fang,HAN Li,ZHANG Dingkun,YANG Yingguang,TANG Yixuan,QIN Chunfeng.Formulation and Technology of Huangxin Dispersible Tablets[J].Liaoning Journal of Traditional Chinese Medicine,2014(11):2422-2425. |
| |
| Authors: | ZHANG Fang HAN Li ZHANG Dingkun YANG Yingguang TANG Yixuan QIN Chunfeng |
| |
| Institution: | ( Key Laboratory of System Research and Development of traditional Chinese Medicine Resources of Chengdu University of Traditional Chinese Medicine, Chengdu 611137, Sichuan, China) |
| |
| Abstract: | Objective：To optimize the formulation and technology of Huangxin dispersible tablets. Methods：The single factor method was used and the disintegration time was used as index. The formulation and technology of Huangxin dispersible tablets was selected and the dissolution rate was determined. Results ： The optimal condition of Huangxin dispersible tablets were as fol- lows ：50% baicalin,12.5% andrographolide,MCC22.5% ,micro - silica gel5% ; the disintegration time was（75 ± 4） s. The dis- solution rate and degree of baicalin and andrographolide in Huangxin dispersible tablets were higher than Huangxin capsules. Con- clusion：This preparation of Huangxin dispersible tablets is reasonable, and the technology is feasible. |
| |
| Keywords: | Huangxin dispersible tablet formulation and technology single factor method |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
