早产儿视网膜病发病率及高危因素分析

目的观察早产儿视网膜病变（ROP）的发病情况,同时分析其发病相关危险因素。方法回顾性分析2007年4月～2009年4月在本院新生儿重症监护室（NICU）住院的201例符合ROP筛查标准的患儿。结果 ROP发病率为19.1%,不同出生体重（BW）组间ROP发病率差异有统计学意义（P〈0.05）,不同孕周组间ROP发病率差异有统计学意义（P〈0.01）。Logistic回归分析结果表明,低出生体重（LBW）、低胎龄（SGA）、呼吸暂停、代谢性酸中毒是形成ROP的高危因素。结论对有高危因素的早产儿应该进行ROP筛查,临床上早期诊断、早期治疗是降低ROP危害的关键。

The incidence and high risk factors analysis of retinopathy in prematurity

Objective To observe the present incidence of retinopathy of premature infants who admitted to the first People′s Hospital of Lianyungang,and to analyze the possible risk factors associated with the development of ROP.Methods 201 cases were retrospectively analyzed in the NICU of hospital from January 2007 to January 2009 and all children patients were found compatible with the ROP screening standard.Results The overall incidence of ROP was 19.1%,the differences in prevalence of ROP among different birth weight groups and different gestational age groups were all statistical significant(all P < 0.05);low birth weight,small gestational age,apnea,metabolic acidosis were the high risk factors of ROP according to Logistic regression analysis.Conclusion These premature infants with risk factors should take regular ROP examination.Early diagnosis and cure are the keys to reduce the risk of ROP.