经皮激光椎间盘汽化减压术联合胶原酶盘外溶核术治疗腰椎间盘突出症103例的临床疗效分析

目的：研究和分析经皮激光椎间盘汽化减压术（percutaneous laser disc decompression, PLDD）联合胶原酶盘外溶核术治疗腰椎间盘突出症的临床疗效。方法：以2011年1月—2014年1月我院收治的198例腰椎间盘突出症患者为研究对象，分为施行PLDD联合胶原酶盘外溶核术治疗的观察组（103例）和仅施行PLDD治疗的对照组（95例）。对这些患者均进行术后随访3~12个月，并按改良的MacNab疗效评定标准分析、比较PLDD联合胶原酶盘外溶核术与单用PLDD治疗的临床疗效。结果：观察组的近、中、远期有效率均显著高于对照组（均P＜0.05）。结论：PLDD联合胶原酶盘外溶核术治疗较单用PLDD治疗更有效，是治疗腰椎间盘突出症的有效方法。

Analysis of clinical curative effect of percutaneous laser disc decompression combined with collagenase chemonucleolysis on 103 cases with lumbar disc herniation

Objective:To study and analyze the clinical efifcacy of percutaneous laser disc decompression (PLDD) combined with collagenase chemonucleolysis in the treatment of lumbar disc herniation. Methods:One hundred and ninety-eight cases of patients with lumbar disc herniation treated in our hospital from January, 2011 to January, 2014 were divided an observation group (103 cases, underwent PLDD combined with collagenase chemonucleolysis) and a control group (95 cases, underwent only PLDD) and were followed up for 3 ~ 12 months. Their clinical efficacy was evaluated based on a modified MacNab evaluation criteria and then compared between two groups. Results:The effective rates of the near-, medium-and long-term were signiifcantly higher in the observation group than in the control group (P<0.05). Conclusion:PLDD combined with collagenase chemonucleolysis is more effective than only use of PLDD, so it is an effective therapy for lumbar disc herniation.