| 他克莫司软膏治疗口腔扁平苔藓的短期疗效评价 |
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| 引用本文： | 左雯鑫,秦念红,李晓宇,徐铁华. 他克莫司软膏治疗口腔扁平苔藓的短期疗效评价[J]. 口腔医学研究, 2011, 27(5): 422-424 |
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| 作者姓名： | 左雯鑫 秦念红 李晓宇 徐铁华 |
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| 作者单位： | 暨南大学第二临床医学院深圳市人民医院口腔医学中心,广东,深圳,518020 |
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| 摘 要： | 目的：观察0．1％他克莫司软膏治疗口腔扁平苔藓的疗效及探讨REU评分系统应用于临床疗效评价的可行性。方法：对56例经病理诊断为1：3腔黏膜扁平苔藓的患者予以0．1％他克莫司软膏治疗4周，采用REU评分系统比较治疗前后临床症状和体征改善情况。结果：他克莫司软膏治疗口腔扁平苔藓总有效率为80．35％，56例患者治疗前REU评分值为（21．98±6．45），治疗后为（15．03±5．47），治疗前后评分值差异有统计学意义（P＜0．01）。结论：他克莫司软膏治疗口腔扁平苔藓具有较好的短期疗效，REU评分系统是一种较为客观、精确的临床疗效评
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| 关 键 词： | 他克莫司 口腔扁平苔藓 REU评分系统 |
Short-term Clinical Evaluation of Tacrolimus 0.1% Ointment for Treatment of Oral Lichen Planus |
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| ZUO Wen-xin,QIN Nian-hong,LI Xiao-yu,et al.. Short-term Clinical Evaluation of Tacrolimus 0.1% Ointment for Treatment of Oral Lichen Planus[J]. Journal of Oral Science Research, 2011, 27(5): 422-424 |
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| Authors: | ZUO Wen-xin QIN Nian-hong LI Xiao-yu et al. |
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| Affiliation: | ZUO Wen-xin,QIN Nian-hong,LI Xiao-yu,et al.Department of Stomatology,2nd Clinical Medicine College,Jinan University,Shenzhen People's Hospital,Shenzhen 518020 |
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| Abstract: | Objective:To evaluate the clinical efficacy of tacrolimus 0.1% ointment in patients with OLP using REU scoring system.Methods:An open trial included 56 patients with the diagnosis of erosive and ulcerative OLP.All patients received 4 weeks of treatment of tacrolimus 0.1% ointment.Meanwhile the REU scoring system was utilized to compare the symptoms before and after treatment.Results:45(80.35%) patients demonstrated rapid relief of signs and symptoms within 4 weeks threapy.There was statistically significant... |
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| Keywords: | Tacrolimus Oral lichen planus REU scoring system |
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